Diagnosis
There
is no specific laboratory or imaging test which can be performed to
diagnose irritable bowel syndrome. Diagnosis of IBS involves excluding
conditions which produce IBS-like symptoms, and then following a procedure
to categorize the patient's symptoms.
Because
there are many causes of diarrhea and IBS-like symptoms, the American
Gastroenterological Association has published a set of guidelines for
tests to be performed to diagnose other conditions which may have symptoms
similar to IBS. These include gastrointestinal infections, lactose intolerance
and Coeliac disease. Research has suggested that these guidelines are
not always followed. Once other causes have been excluded, the diagnosis
of IBS is performed using a diagnostic algorithm. Well-known algorithms
include the Manning Criteria, the obsolete Rome I and II criteria, the
Kruis Criteria, and studies have compared their reliability. The more
recent Rome III Process was published in 2006. Physicians may choose
to use one of these guidelines, or may simply choose to rely on their
own anecdotal experience with past patients. The algorithm may include
additional tests to guard against mis-diagnosis of other diseases as
IBS. Such "red flag" symptoms may include weight loss, GI
bleeding, anemia, or nocturnal symptoms. However, researchers have noted
that red flag conditions may not always contribute to accuracy in diagnosis
— for instance, as many as 31% of IBS patients have blood in their
stool.
The
diagnostic algorithm identifies a name which can be applied to the patient's
condition based on the combination of the patient's symptoms of diarrhea,
abdominal pain, and constipation. For example, the statement "50%
of returning travelers had developed functional diarrhea while 25% had
developed IBS" would mean that half the travelers had diarrhea
while a quarter had diarrhea with abdominal pain. While some researchers
believe this categorization system will help physicians understand IBS,
others have questioned the value of the system and suggested that all
IBS patients have the same underlying disease but with different symptoms.
Misdiagnosis
Published
research has demonstrated that some poor patient outcomes are due to
treatable causes of diarrhea being mis-diagnosed as IBS. Common examples
include infectious diseases, celiac disease, parasites, food allergies
(though considered controversial), and lactose intolerance. See List
of causes of diarrhea for other conditions which can cause diarrhea.
Celiac
disease in particular is often misdiagnosed as IBS. The American College
of Gastroenterology recommends that all patients with symptoms of IBS
be tested for celiac disease. Chronic use of certain sedative-hypnotic
drugs especially the benzodiazepines may cause irritable bowel like
symptoms which can lead to a misdiagnosis of irritable bowel syndrome.