Screening
Although not all people with Tourette's
have comorbid conditions, most Tourette's patients presenting for clinical
care at specialty referral centers may exhibit symptoms of other conditions
along with their motor and phonic tics.[30] Associated conditions include
attention-deficit hyperactivity disorder (ADD or ADHD), obsessive–compulsive
disorder (OCD), learning disabilities and sleep disorders.[3] Disruptive
behaviors, impaired functioning, or cognitive impairment in patients
with comorbid Tourette's and ADHD may be accounted for by the comorbid
ADHD, highlighting the importance of identifying and treating comorbid
conditions.[22][28][49] Disruption from tics is commonly overshadowed
by comorbid conditions that present greater interference to the child.[6]
Tic disorders in the absence of ADHD do not appear to be associated
with disruptive behavior or functional impairment,[4] while impairment
in school, family, or peer relations is greater in patients who have
more comorbid conditions and often determines whether therapy is needed.[14]
Because comorbid conditions such as
OCD and ADHD can be more impairing than tics, these conditions are included
in an evaluation of patients presenting with tics. "It is critical
to note that the comorbid conditions may determine functional status
more strongly than the tic disorder," according to Samuel Zinner,
MD.[6] The initial assessment of a patient referred for a tic disorder
should include a thorough evaluation, including a family history of
tics, ADHD, obsessive–compulsive symptoms, and other chronic medical,
psychiatric and neurological conditions. Children and adolescents with
TS who have learning difficulties are candidates for psychoeducational
testing, particularly if the child also has ADHD.[45] Undiagnosed comorbid
conditions may result in functional impairment, and it is necessary
to identify and treat these conditions to improve functioning. Complications
may include depression, sleep problems, social discomfort and self-injury